NATURE OF SPONTANEOUS MUTATIONS DURING VEGETATIVE GROWTH IN SCHIZOSACCHAROMYCES POMBE

被引：13

作者：

LOPRIENO, N

BONATTI, S

ABBONDANDOLO, A

GUGLIELMINETTI, R

机构：

[1] Istituto di Genetica dell'Università, Pisa

[2] Laboratorio di Mutagenesi e Differenziamento del C.N.R., Pisa

来源：

MOLECULAR AND GENERAL GENETICS | 1969年 / 104卷 / 01期

关键词：

D O I：

10.1007/BF00277361

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fifty five purple spontaneous mutants of the haploid fission yeast Schizosaccharomyces pombe have been isolated and distributed, by genetic analyses, between two loci (ad-6 and ad-7) which control two independent steps in the purine biosynthesis. The molecular nature of these mutants has been determined by both their physiological behaviour (leakiness, temperature-sensitivity, pH-sensitivity) and their interallelic complementation ability. It is concluded that during the mitotic cycle the large majority of spontaneous mutations are base-pair substitutions. © 1969 Springer-Verlag.

引用

页码：40 / +

页数：1

共 38 条

[1] AMINO ACID SUBSTITUTIONS IN MUTANT FORMS OF HISTIDINOL DEHYDROGENASE FROM NEUROSPORA CRASSA [J].