LINKAGE AND SEQUENCE CONSERVATION OF THE X-LINKED GENES DXS253E (P3) AND DXS254E (GDX) IN MOUSE AND MAN

被引：20

作者：

FILIPPI, M

TRIBIOLI, C

TONIOLO, D

机构：

[1] Istituto di Genetica Biochimica ed Evoluzionistica, CNR, 27100 Pavia

来源：

GENOMICS | 1990年 / 7卷 / 03期

关键词：

D O I：

10.1016/0888-7543(90)90184-V

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Lambda G28, a mouse genomic clone homologous to the human P3 gene and associated with a CpG island, also hybridizes to human probes for the neighboring GdX gene. The two genes, P3 and GdX (DXS253E and DXS254E), physically linked on the human X chromosome, lie within a similar physical distance on the mouse X chromosome. The CpG island corresponds to that at the 5′ of the human GdX gene. The relative orientation of the two genes is the same. The DNA sequence in coding and noncoding regions is very conserved. © 1990.

引用

页码：453 / 457

页数：5

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