CARDIAC GANGLIONITIS ASSOCIATED WITH SUDDEN UNEXPECTED DEATH

被引:58
作者
JAMES, TN
ZIPES, DP
FINEGAN, RE
EISELE, JW
CARTER, JE
机构
[1] INDIANA UNIV, MED CTR, INDIANAPOLIS, IN 46204 USA
[2] SANTA CRUZ HOSP, SANTA CRUZ, CA USA
关键词
D O I
10.7326/0003-4819-91-5-727
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In a postmortem study of the hearts of two young women who died suddenly and unexpectedly, we found a remarkably similar and distinctive ganglionitis, predominantly in the region of the sinus node. Both women had ventricular fibrillation at the time of collapse. Vesicular neuritis and older neural degeneration were present in other regions of the heart. Except for focal fibromuscular dysplasia of the sinus node artery and atrioventricular node artery of one heart, there was no other significant anatomic abnormality in either heart. The functional significance of this cardiac ganglionitis is unclear, but its location in and around the conduction system makes it a possible cause of the fatal electrical instability. Recognition that ganglionitis of the heart may be associated with sudden death should stimulate a number of additionally useful studies.
引用
收藏
页码:727 / 730
页数:4
相关论文
共 17 条
[1]   HERPESVIRUS-INFECTION OF THE ESOPHAGUS AND OTHER VISCERAL ORGANS IN ADULTS - INCIDENCE AND CLINICAL SIGNIFICANCE [J].
BUSS, DH ;
SCHARYJ, M .
AMERICAN JOURNAL OF MEDICINE, 1979, 66 (03) :457-462
[2]   4 QUESTIONS ABOUT PROTEIN DIETS [J].
FELIG, P .
NEW ENGLAND JOURNAL OF MEDICINE, 1978, 298 (18) :1025-1026
[3]  
FRASER GR, 1964, Q J MED, V33, P361
[4]   NATURE OF HERPES ZOSTER - A LONG-TERM STUDY AND A NEW HYPOTHESIS [J].
HOPESIMPSON, RE .
PROCEEDINGS OF THE ROYAL SOCIETY OF MEDICINE-LONDON, 1965, 58 (01) :9-+
[5]   EPIDEMIOLOGY OF VIRUSES - ANTIGENICITY AND EVOLUTION [J].
HOPESIMPSON, RE .
PROCEEDINGS OF THE ROYAL SOCIETY OF MEDICINE-LONDON, 1969, 62 (11P1) :1138-+
[6]  
JAMES TN, 1961, ANAT REC, V141, P109, DOI 10.1002/ar.1091410205
[7]   DE SUBITANEIS MORTIBUS .30. OBSERVATIONS ON PATHOPHYSIOLOGY OF LONG QT SYNDROMES WITH SPECIAL REFERENCE TO NEUROPATHOLOGY OF HEART [J].
JAMES, TN ;
FROGGATT, P ;
ATKINSON, WJ ;
LURIE, PR ;
MCNAMARA, DG ;
MILLER, WW ;
SCHLOSS, GT ;
CARROLL, JF ;
NORTH, RL .
CIRCULATION, 1978, 57 (06) :1221-1231
[8]   DE-SUBITANEIS-MORTIBUS .17. MULTIFOCAL STENOSES DUE TO FIBROMUSCULAR DYSPLASIA OF SINUS NODE ARTERY [J].
JAMES, TN ;
MARSHALL, TK .
CIRCULATION, 1976, 53 (04) :736-742
[9]   SUDDEN DEATH IN YOUNG ATHLETES [J].
JAMES, TN ;
FROGGATT, P ;
MARSHALL, TK .
ANNALS OF INTERNAL MEDICINE, 1967, 67 (05) :1013-+