THE CONTINUED SEARCH FOR EVIDENCE OF RETROVIRAL INFECTION IN SCHIZOPHRENIC-PATIENTS

被引:7
作者
COGGIANO, MA
ALEXANDER, RC
KIRCH, DG
WYATT, RJ
KULAGA, H
机构
[1] Neuropsychiatry Branch, National Institute of Mental Health (NIMH), NIMH Neuroscience Center, SE Washington, DC 20032, 2700 Martin L. King, Jr. Ave
关键词
RETROVIRUS; (SCHIZOPHRENIA);
D O I
10.1016/0920-9964(91)90082-3
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Retroviral infection has been proposed as an etiologic factor in schizophrenia. In an effort to unmask a latent retrovirus, short term cultures of peripheral lymphocytes from 15 schizophrenic subjects and nine normal controls were exposed to ionizing radiation and co-cultured with indicator cells. Reverse transcriptase activity. a marker of retroviral infection, could not be detected in any of the cultures. Our findings are further evidence against a role for retroviral infection in the etiology of schizophrenia.
引用
收藏
页码:243 / 247
页数:5
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