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PRELIMINARY STUDIES OF THE MODE OF ACTION OF ARILDONE, A NOVEL ANTI-VIRAL AGENT

被引：20
作者：
KUHRT, MF
FANCHER, MJ
JASTY, V
PANCIC, F
CAME, PE
机构：
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1979年 / 15卷 / 06期
关键词：
D O I：
10.1128/AAC.15.6.813
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Arildone (also known as Win 38020), a novel aryl diketone, inhibited replication of herpes simplex virus type 2 in tissue culture by interfering with an event that occurs prior to 6 h postinfection. The inhibition could be paritally reversed by washing. Although the exact mechanism of action is unknown, neither viral deoxyribonucleic acid nor viral proteins were synthesized in the presence of arildone.
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页码：813 / 819
页数：7
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