EFFICIENT ASYMMETRIC-SYNTHESIS OF OPTICALLY PURE TERTIARY MONO AND DIPHOSPHINE LIGANDS

被引：282

作者：

JUGE, S ^{[1
]}

STEPHAN, M ^{[1
]}

LAFFITTE, JA ^{[1
]}

GENET, JP ^{[1
]}

机构：

[1] SOC NATL ELF AQUITAINE,RECH LACQ GRP,F-64170 ARTIX,FRANCE

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(00)97063-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The oxazaphopholidine borano complex 3, prepared in one step from ephedrine, reacts with alkyl and aryl lithium compounds to afford regio and stereoselectively the corresponding aminophosphine complexes 4. Acid methanolysis of 4 leads to the phosphinite borane complexes 5 which are used for the preparation of the mono and diphosphine boranes 6, 8, and subsequently the corresponding phosphines 7, 9 alter decomplexation with Et2NH. The preparation of (+) and (-)-PAMP 7a, DIPAMP 9a or β-BNPE 9b from the same complex 3 is described. © 1990.

引用

页码：6357 / 6360

页数：4

共 25 条

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