SECONDARY METABOLITES BY CHEMICAL-SCREENING .2. AMYCIN-A AND AMYCIN-B, 2, NOVEL NIPHIMYCIN ANALOGS ISOLATED FROM A HIGH PRODUCER STRAIN OF ELAIOPHYLIN AND NIGERICIN

被引：45

作者：

GRABLEY, S ^{[1
]}

HAMMANN, P ^{[1
]}

RAETHER, W ^{[1
]}

WINK, J ^{[1
]}

ZEECK, A ^{[1
]}

机构：

[1] STATE UNIV GRONINGEN,INST ORGAN CHEM,9700 AB GRONINGEN,NETHERLANDS

来源：

JOURNAL OF ANTIBIOTICS | 1990年 / 43卷 / 06期

关键词：

D O I：

10.7164/antibiotics.43.639

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Two novel natural niphimycin analogs, amycins A (5) and B (3) were isolated from the culture broth of the Streptomyces sp. DSM 3816 by chemical screening methods. In addition this strain produces the antibiotics niphimycin (4), elaiophylin (2) and nigericin (1). Fermentation, isolation, structure elucidation and biological activity of the amycins are described. © 1990, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：639 / 647

页数：9

共 30 条

[1]

ARAI M, 1960, J ANTIBIOT, V13, P46

[2]

ARAI M, 1968, ARZNEI-FORSCHUNG, V18, P1396

[3] ISOLATION OF NEOCOPIAMYCIN A FROM STREPTOMYCES-HYGROSCOPICUS VAR CRYSTALLOGENES, THE COPIAMYCIN SOURCE [J].

ARAI, T ;

UNO, J ;

HORIMI, I ;

FUKUSHIMA, K .

JOURNAL OF ANTIBIOTICS, 1984, 37 (02) :103-109

[4]

ARCAMONE F. M., 1959, GIORN MICROBIOL, V7, P207

[5] ON THE STRUCTURE ELUCIDATION OF NIPHIMYCIN .1. PURIFICATION AND CHARACTERIZATION OF THE NIPHIMYCIN-I-ALPHA AND NIPHIMYCIN-I-BETA - DEGRADATION BY NITRIC-ACID [J].

BASSI, L ;

JOOS, B ;

GASSMANN, P ;

KAISER, HP ;

LEUENBERGER, H ;

KELLERSCHIERLEIN, W .

HELVETICA CHIMICA ACTA, 1983, 66 (01) :92-117

[6]

BERGY ME, 1972, J ANTIBIOT, V25, P39, DOI 10.7164/antibiotics.25.39

[7]

BLINOV N. O., 1967, ANTIBIOTIKI, V12, P867

[8] SECONDARY METABOLITES BY CHEMICAL-SCREENING .1. CALCIUM 3-HYDROXYQUINOLINE-2-CARBOXYLATE FROM A STREPTOMYCES [J].

BREIDINGMACK, S ;

ZEECK, A .

JOURNAL OF ANTIBIOTICS, 1987, 40 (07) :953-960

[9]

BREIDINGMACK S, 1984, THESIS U GOTTINGEN

[10] METABOLIC PRODUCTS OF MICROORGANISMS .222. BETA-OXOTRYPTAMINE DERIVATIVES ISOLATED FROM STREPTOMYCES-RAMULOSUS [J].

CHEN, Y ;

ZEECK, A ;

CHEN, ZX ;

ZAHNER, H .

JOURNAL OF ANTIBIOTICS, 1983, 36 (07) :913-915

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