SITE SPECIFIC ENDONUCLEASE FROM FUSOBACTERIUM NUCLEATUM

被引：53

作者：

LUI, ACP

MCBRIDE, BC

VOVIS, GF

SMITH, M

机构：

[1] UNIV BRITISH COLUMBIA, DEPT MICROBIOL, VANCOUVER V6T 1W5, BC, CANADA

[2] ROCKEFELLER UNIV, NEW YORK, NY 10021 USA

来源：

NUCLEIC ACIDS RESEARCH | 1979年 / 6卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1093/nar/6.1.1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four different isolates of Fusobacterium nucleatum (A,C, D and E) contain restriction endonucleases of differing specificity. Whilst many of the endonucleases are isochizomers of known enzymes, two novel activities are Fnu DII which recognizes and cleaves the sequence5'-CG↓CG-3'3'-GC↑GC-5' and Fnu El which recognizes and cleaves the sequence 5'-GA↓TC-3'3'-CT↑AG-5' irrespective of the extent of methylation of the adenine residues. © 1979 Information Retrieval Limited.

引用

页码：1 / 15

页数：15

共 16 条

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