ONE POT SOLUTION SYNTHESIS OF CYCLIC OLIGODEOXYRIBONUCLEOTIDES

被引：49

作者：

CAPOBIANCO, ML ^{[1
]}

CARCURO, A ^{[1
]}

TONDELLI, L ^{[1
]}

GARBESI, A ^{[1
]}

BONORA, GM ^{[1
]}

机构：

[1] UNIV PADUA, CTR STUDI BIOPOLIMERI, DIPARTIMENTO CHIM ORGAN, I-35131 PADUA, ITALY

来源：

NUCLEIC ACIDS RESEARCH | 1990年 / 18卷 / 09期

关键词：

D O I：

10.1093/nar/18.9.2661

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Several cyclic oligodeoxynucleotides with different base composition and size have been prepared from 5′,3′-unprotected linear precursors, using a bifunctional phosphorylating reagent. The final deprotected ollgomers have been characterized by 1H- and 31P-NMR. The present procedure is particularly useful for millimolar scale syntheses. © 1990 Oxford University Press.

引用

页码：2661 / 2669

页数：9

共 16 条

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