AT WHAT AGE IS THE DEVELOPING CEREBRAL-CORTEX OF THE RAT COMPARABLE TO THAT OF THE FULL-TERM NEWBORN HUMAN BABY

被引:456
作者
ROMIJN, HJ [1 ]
HOFMAN, MA [1 ]
GRAMSBERGEN, A [1 ]
机构
[1] STATE UNIV GRONINGEN HOSP,DEPT DEV NEUROL,9713 EZ GRONINGEN,NETHERLANDS
关键词
CEREBRAL CORTEX; DEVELOPMENT; PERINATOLOGY; RAT; HUMAN;
D O I
10.1016/0378-3782(91)90044-4
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
By means of a comparative study of experimental data from the literature we estimated at what age the rat cerebral cortex corresponds to that of the full-term newborn human infant with regard to the degree of maturation. As a result of this study we suggest that the 12-13-day-old rat pup fulfills this criterion. This finding should be of use to scientist who use the rat for studying certain processes assumed to occur in the human cerebral cortex around full-term birth.
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页码:61 / 67
页数:7
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