CREATINE-KINASE ISOFORMS - INVESTIGATION OF INHIBITORS OF INVITRO DEGRADATION AND ESTABLISHMENT OF A REFERENCE RANGE

被引：12

作者：

DAVIES, J

REYNOLDS, T

PENNEY, MD

机构：

[1] Department Chemical Pathology, Royal Gwent Hospital, Newport

来源：

ANNALS OF CLINICAL BIOCHEMISTRY | 1992年 / 29卷

关键词：

MYOCARDIAL INFARCTION; LABORATORY DIAGNOSIS; CARBOXYPEPTIDASE; HIGH VOLTAGE ELECTROPHORESIS;

D O I：

10.1177/000456329202900214

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The in vitro stability of creatine kinase isoforms was examined by separation with high voltage electrophoresis. The effect of inhibitors of carboxypeptidase was evaluated. Preservation of samples is essential to inhibit in vitro changes in isoform pattern. EDTA at a final concentration of 15 mmol/L is recommended. Using appropriately preserved samples, normal reference intervals for the MM isoforms have been established.

引用

页码：202 / 205

页数：4

共 16 条

[1] CHANGING PRESENTATION OF MYOCARDIAL-INFARCTION WITH INCREASING OLD-AGE
BAYER, AJ
CHADHA, JS
FARAG, RR
PATHY, MSJ
[J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1986, 34 (04) : 263 - 266
[2] SERUM CREATINE-KINASE MM SUB-BAND DETERMINATION BY ISOELECTRIC-FOCUSING - A POTENTIAL METHOD FOR THE MONITORING OF MYOCARDIAL-INFARCTION
CHAPELLE, JP
[J]. CLINICA CHIMICA ACTA, 1984, 137 (03) : 273 - 281
[3] CHAPELLE JP, 1980, CLIN CHEM, V26, P457
[4] DIAGNOSTIC CHANGES IN PLASMA CREATINE-KINASE ISOFORMS EARLY AFTER THE ONSET OF ACUTE MYOCARDIAL-INFARCTION
JAFFE, AS
SEROTA, H
GRACE, A
SOBEL, BE
[J]. CIRCULATION, 1986, 74 (01) : 105 - 109
[5] KESHGEGIAN AA, 1988, CLIN CHEM, V34, P1067
[6] MM-CK SUBTYPES DIAGNOSE REPERFUSION EARLY AFTER MYOCARDIAL-INFARCTION
MORELLI, RL
EMILSON, B
RAPAPORT, E
[J]. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1987, 293 (03) : 139 - 149
[7] SERUM CREATINE-KINASE MM ISOENZYME SUB-BANDS AFTER ACUTE MYOCARDIAL-INFARCTION IN MAN
MORELLI, RL
CARLSON, CJ
EMILSON, B
ABENDSCHEIN, DR
RAPAPORT, E
[J]. CIRCULATION, 1983, 67 (06) : 1283 - 1289
[8] NOHARA R, 1988, CLIN CHEM, V34, P235
[9] EARLY DIAGNOSIS OF ACUTE MYOCARDIAL-INFARCTION BASED ON ASSAY FOR SUBFORMS OF CREATINE KINASE-MB
PULEO, PR
GUADAGNO, PA
ROBERTS, R
SCHEEL, MV
MARIAN, AJ
CHURCHILL, D
PERRYMAN, MB
[J]. CIRCULATION, 1990, 82 (03) : 759 - 764
[10] PULEO PR, 1989, CLIN CHEM, V35, P1452

← 1 2 →