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STUDIES ON THE ANTIULCEROGENIC ACTIVITY OF THE ESSENTIAL OIL OF HYPTIS-MUTABILIS BRIQ IN RATS
被引：20
作者：
BARBOSA, PPP
RAMOS, CP
机构：
[1] Departamento de Fisiologia, Centro de Ciencias Biológicas, Universidade Federal de Alagoas, Maceió, Alagoas
关键词：
GASTRIC ULCER;
GASTRITIS;
HAEMORRHAGIAE;
VOLATILE OIL;
HYPTIS-MUTABILIS;
D O I：
10.1002/ptr.2650060214
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The volatile oil of Hyptis mutabilis, Briq. was investigated for its ability to prevent or reduce the formation of ulcerations in the gastric mucosa of male rats induced by indomethacin subcutaneous injection. When previously administered (p.o. and i.p.) the oil (F1473; 50-100 mg/kg) significantly reduced gastric alterations produced by indomethacin in a dose-dependent fashion. However, the mechanism of action of this plant oil is still unknown.
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页码：114 / 115
页数：2
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