ACTIVE-TRANSPORT OF URIDINE THROUGH A LIQUID ORGANIC MEMBRANE MEDIATED BY PHENYLBORONIC ACID AND DRIVEN BY A FLUORIDE-ION GRADIENT

被引：73

作者：

PAUGAM, MF ^{[1
]}

SMITH, BD ^{[1
]}

机构：

[1] UNIV NOTRE DAME,DEPT CHEM & BIOCHEM,NOTRE DAME,IN 46556

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 23期

关键词：

ACTIVE TRANSPORT; RIBONUCLEOSIDE; BORONIC ACID; FLUORIDE; LIQUID ORGANIC MEMBRANE;

D O I：

10.1016/S0040-4039(00)79210-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Phenylboronic acid simultaneously co-transports the ribonucleoside, uridine, and fluoride ion through an organic liquid membrane. The transport mechanism involves self-assembly of a lipophilic ion-pair comprising of phenylboronic acid, fluoride ion, uridine and tetralkylammonium cation. Active uridine transport (i.e. uphill transport against a concentration gradient) occurs in the direction of a fluoride ion concentration gradient.

引用

页码：3723 / 3726

页数：4

共 15 条

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