SYNTHESIS OF NN-DI-(2-CHLORETHYL)[3,5-3H2]ANILINE OF HIGH SPECIFIC ACTIVITY

被引：7

作者：

BALL, CR

WADE, R

机构：

[1] Chester Beatty Research Institute, Institute of Cancer Research, Royal Cancer Hospital

[2] CIBA Laboratories Ltd., Horsham

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1968年 / 11期

关键词：

D O I：

10.1039/j39680001338

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of NN-di-(2-chloroethyl)aniline specifically tritiated in the positions meta to the nitrogen mustard group by catalytic halogen-tritium exchange with the 3,5-di-iodo-derivative is described.

引用

页码：1338 / &

共 5 条

[1] STUDIES OF MODE OF ACTION OF TUMOUR-GROWTH-INHIBITING ALKYLATING AGENTS .5. METABOLISM OF 2-CHLOROETHYLARYLAMINES
ROBERTS, JJ
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[J]. BIOCHEMICAL PHARMACOLOGY, 1963, 12 (12) : 1321 - &
[2] Some Derivates of 3-ethylpyridine and 2 3-furano(2'3')pyridine
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Watt, JS
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1934, : 1536 - 1543
[3] WARWICK GP, IN PRESS
[4] CURE OF MICE BEARING ADVANCED PLASMA CELL TUMOURS WITH ANILINE MUSTARD
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CONNORS, TA
[J]. NATURE, 1965, 206 (4985) : 689 - &
[5] Processing of p-nitranilin on tri-iodine- and tetra-iodine-benzenes, on penta-iodinebenzene, as well as on all intermediate products leading to those compounds.
Willgerodt, C
Arnold, E
[J]. BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT, 1901, 34 : 3343 - 3354

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