CELL-CULTURE ASSAY FOR THE DETECTION OF MYCOTOXINS .1. INVESTIGATIONS WITH PURE TOXINS

被引：19

作者：

LOMPE, A ^{[1
]}

MILCZEWSKI, KEV ^{[1
]}

机构：

[1] INST MIKROBIOL BUNDESANSTALT MILCHFORSCH,D-2300 KIEL,FED REP GER

来源：

ZEITSCHRIFT FUR LEBENSMITTEL-UNTERSUCHUNG UND-FORSCHUNG | 1979年 / 169卷 / 04期

关键词：

D O I：

10.1007/BF01193788

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

For the detection of mycotoxins by a biological assay cells were seeded in Microtiter-plates together with toxin. After 24 h and 6 days of culture cells were examined visually for cytocidal effects, growth inhibition, and morphological aberrations. Three human and 2 porcine cell-lines were compared as to their reaction with 16 mycotoxins and 9 organic chemicals. The results indicate that the toxin-activating systems differ with type and origin of cells. This suggests the use of several selected cell-lines in parallel for testing of microbially derived food additives for possible contamination by mycotoxins. © 1979 J. F. Bergmann Verlag.

引用

页码：249 / 254

页数：6

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