NEW SYNTHETIC INTERMEDIATE FOR TRANS-8-METHYLHYDRINDANONES

被引：13

作者：

YAMADA, H ^{[1
]}

SHIMIZU, K ^{[1
]}

NISAR, M ^{[1
]}

TAKAHASHI, T ^{[1
]}

TSUJI, J ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,TOKYO 152,JAPAN

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 17期

关键词：

D O I：

10.1016/S0040-4039(00)97374-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of 1-acetyl-8-methylhydrindan-5-one (3) by the conjugate addition-enolate protonation of the 3-alkyl-2-methyl-1-acetylcyclopentene 1 followed by the cyclization of the cyanohydrin ether, and discussions for the diastereoselectivity in the enolate protonation based on MM2 calculations are presented. © 1990.

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页码：2407 / 2410

页数：4

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