LATE ONSET PRIMARY SYSTEMIC CARNITINE DEFICIENCY EXACERBATED BY CARNITINE-FREE PARENTERAL-NUTRITION

被引：4

作者：

BUCHMAN, AL

VINTERS, HV

DIETHELM, S

AMENT, ME

VERITY, MA

机构：

[1] Division of Pediatric Gastroenterolgy/Nutrition, UCLA Medical Center, Los Angeles, CA

[2] Division of Neuropathology, UCLA Medical Center, Los Angeles, CA

[3] Division of Anatomic Pathology, UCLA Medical Center, Los Angeles, CA

来源：

CLINICAL NUTRITION | 1992年 / 11卷 / 06期

关键词：

D O I：

10.1016/0261-5614(92)90089-9

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

We describe a 21-year-old male with previously normal plasma total and free carnitine levels who developed a deficiency manifest by decreased plasma and muscle total and free carnitine, decreased urine carnitine, severe hepatic steatosis, mediastinal lipomatosis, progressively impaired triglyceride clearance, myopathy and intermittent hypoglycemia. This case demonstrates that systemic carnitine deficiency may occur in some patients receiving long term carnitine-free TPN. Carnitine may be an essential element of the diet in this patient population.

引用

页码：368 / 372

页数：5

共 18 条

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