IMMUNOHISTOCHEMICAL DEMONSTRATION OF ANDROGEN RECEPTORS ON TESTICULAR BLOOD-VESSELS

被引：29

作者：

BERGH, A ^{[1
]}

DAMBER, JE ^{[1
]}

机构：

[1] UMEA UNIV, DEPT UROL & ANDROL, S-90187 UMEA, SWEDEN

来源：

INTERNATIONAL JOURNAL OF ANDROLOGY | 1992年 / 15卷 / 05期

关键词：

ANDROGEN RECEPTOR; BLOOD VESSELS; TESTICULAR MACROPHAGES; TESTIS;

D O I：

10.1111/j.1365-2605.1992.tb01357.x

中图分类号：

R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

摘要：

Using an antiserum directed against the human and rat androgen receptor we have used immunohistochemistry to demonstrate that nuclear androgen receptors are present in the muscular layer of almost all arteries within the rat testis. These receptors are apparently influenced by testosterone. They disappear after Leydig cell depletion induced by ethanedimethane sulphonate (EDS) and return after testosterone treatment. It is suggested that testicular blood vessels could be a target-organ for androgens and may mediate some of the effects of androgens on the testicular microcirculation.

引用

页码：425 / 434

页数：10

共 29 条

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BERGH, A
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[8] TESTICULAR BLOOD-FLOW, VASCULAR-PERMEABILITY, AND TESTOSTERONE PRODUCTION AFTER STIMULATION OF UNILATERALLY CRYPTORCHID ADULT-RATS WITH HUMAN CHORIONIC-GONADOTROPIN
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