PROTEIN ENGINEERING AS A TOOL FOR UNDERSTANDING ELECTRON-TRANSFER

被引：47

作者：

WUTTKE, DS ^{[1
]}

GRAY, HB ^{[1
]}

机构：

[1] CALTECH,BECKMAN INST,PASADENA,CA 91125

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1993年 / 3卷 / 04期

关键词：

D O I：

10.1016/0959-440X(93)90083-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ability to engineer proteins in a specific manner is a powerful tool when applied to the study of biological electron transfer. Mutagenesis, semisynthesis, and site-specific modification have been employed to prepare novel electron-transfer proteins- theoretical and experimental work on these proteins has elucidated the factors that tune active-site redox potentials and spectroscopic features as well as the properties that control electron transfer through polypeptide structures.

引用

页码：555 / 563

页数：9

共 72 条

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