CATHETER-RELATED CUTANEOUS ASPERGILLOSIS COMPLICATED BY FUNGEMIA AND FATAL PULMONARY INFECTION IN AN HIV-POSITIVE PATIENT WITH ACUTE LYMPHOCYTIC-LEUKEMIA

被引：15

作者：

GIRMENIA, C ^{[1
]}

GASTALDI, R ^{[1
]}

MARTINO, P ^{[1
]}

机构：

[1] UNIV ROMA LA SAPIENZA,DEPT HUMAN BIOPATHOL,HAEMATOL SECT,I-00161 ROME,ITALY

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 1995年 / 14卷 / 06期

关键词：

D O I：

10.1007/BF02113431

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A case of intravenous catheter-related cutaneous aspergillosis and Aspergillus fumigatus fungemia in an HIV-positive patient with Burkitt-cell acute lymphocytic leukemia is reported. The patient developed pulmonary aspergillosis with a rapidly fatal outcome despite recovery from neutropenia and improvement of the underlying malignancy. The unusual severity and rapid spread of the infection, despite normal neutrophil count and prompt antifungal therapy, suggest that HIV-related immunocompromise might play a role in the impairment of host defences against Aspergillus infection. Thus catheter-related cutaneous aspergillosis could lead to a severe deep-seated infection in HIV-positive patients.

引用

页码：524 / 526

页数：3

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