INHIBITION OF MAMMALIAN FOLYLPOLYGLUTAMATE SYNTHETASE AND HUMAN DIHYDROFOLATE-REDUCTASE BY 5,8-DIDEAZA ANALOGS OF FOLIC-ACID AND AMINOPTERIN BEARING A TERMINAL L-ORNITHINE

被引：24

作者：

PATIL, SA

SHANE, B

FREISHEIM, JH

SINGH, SK

HYNES, JB

机构：

[1] MED UNIV S CAROLINA,DEPT PHARMACEUT SCI,CHARLESTON,SC 29425

[2] UNIV CALIF BERKELEY,DEPT NUTR SCI,BERKELEY,CA 94720

[3] MED COLL OHIO,DEPT BIOCHEM,TOLEDO,OH 43699

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 07期

关键词：

D O I：

10.1021/jm00127a026

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1559 / 1565

页数：7

共 30 条

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