INACTIVATION OF VESICULAR STOMATITIS-VIRUS BY PHOTOSENSITIZATION FOLLOWING INCUBATION WITH A PYRENE-FATTY-ACID

被引：5

作者：

ABOURABIA, S

FIBACH, E

KOTLER, M

GATT, S

机构：

[1] HEBREW UNIV JERUSALEM, HADASSAH MED SCH, DEPT HEMATOL, IL-91010 JERUSALEM, ISRAEL

[2] HEBREW UNIV JERUSALEM, HADASSAH MED SCH, DEPT MOLEC GENET, IL-91010 JERUSALEM, ISRAEL

[3] HEBREW UNIV JERUSALEM, HADASSAH MED SCH, DEPT MEMBRANE BIOCHEM & NEUROCHEM, IL-91010 JERUSALEM, ISRAEL

来源：

FEBS LETTERS | 1990年 / 270卷 / 1-2期

关键词：

D O I：

10.1016/0014-5793(90)81222-A

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Vesicular stomatitis virus (VSV) was incubated with pyrene dodecanoic acid (P12), a fluorescent derivative of a medium-chain length fatty acid, and subjected to irradiation with a long wavelength ultra-violet light source at 366 nm (UVA). This inactivated the virus, resulting in a drastic decrease of its infectivity. The virus inactivation was proportional to the concentration of the pyrene-fatty acid, the length of exposure of the virus to P12 and the irradiation dose. © 1990.

引用

页码：9 / 10

页数：2

共 18 条

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