EXPRESSION OF GABA-IMMUNOREACTIVITY BY SPINAL MOTONEURONS OF SOME VERTEBRATES

被引：11

作者：

PHILIPPE, E ^{[1
]}

GAULIN, F ^{[1
]}

DELAGRAVE, C ^{[1
]}

GEFFARD, M ^{[1
]}

机构：

[1] CNRS,INST BIOCHIM CELLULAIRE & NEUROCHIM,BORDEAUX,FRANCE

来源：

NEUROSCIENCE LETTERS | 1990年 / 116卷 / 1-2期

基金：

英国医学研究理事会;

关键词：

Immunocytochemistry; Motoneuron; Neuromuscular junction; Phenotype; Spinal cord; Vertebrate; γ-Aminobutyric acid;

D O I：

10.1016/0304-3940(90)90378-M

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Electrophysiological and biochemical investigations have shown that γ-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the vertebrate central nervous system. However, the present study shows that some motoneurons located in the spinal cord of young chickens and adult monkeys display a GABA-like immunoreactivity. The expression of GABA immunoreactivity in vertebrate motoneurons suggests that this inhibitory amino acid is colocalized with acetylcholine and could play a role in the neuromuscular transmission. © 1990.

引用

页码：12 / 16

页数：5

共 16 条

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