IMMUNOSUPPRESSION IN BANCROFTIAN FILARIASIS

被引：26

作者：

GROVE, DI

FORBES, IJ

机构：

[1] CASE WESTERN RESERVE UNIV, DEPT MED, DIV GEOG MED, CLEVELAND, OH 44106 USA

[2] UNIV HOSP CLEVELAND, CLEVELAND, OH 44106 USA

[3] UNIV ADELAIDE, QUEEN ELIZABETH HOSP, DEPT MED, WOODVILLE 5011, S AUSTRALIA, AUSTRALIA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1979年 / 73卷 / 01期

关键词：

D O I：

10.1016/0035-9203(79)90123-8

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Immunological function in Filipino patients with bancroftian filariasis, manifested as either asymptomatic microfilaraemia or chronic obstructive disease, was compared with that found in healthy control subjects living in the same area. As a group, patients with filariasis had raised serum IgG levels, impairment of antibody responses to tetanus and typhoid vaccines, and suppression of delayed hypersensitivity skin reactions to heterologous antigens. This immunosuppression in filariasis may result from antigenic competition and may contribute to the development of secondary infections. © Royal Society of Tropical Medicine and Hygiene.

引用

页码：23 / 26

页数：4

共 25 条

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