COLD REACTIVE ANTI-LYMPHOCYTE ANTIBODIES IN NEUROLOGICAL DISEASES

被引:26
作者
LISAK, RP
MERCADO, F
ZWEIMAN, B
机构
[1] UNIV PENN,SCH MED,DEPT NEUROL,PHILADELPHIA,PA 19174
[2] UNIV PENN,SCH MED,DEPT MED,DIV ALLERGY & IMMUNOL,PHILADELPHIA,PA 19174
关键词
D O I
10.1136/jnnp.42.11.1054
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cold reactive (15°C) antilymphocyte antibodies were detected in the sera of 33% of patients with multiple sclerosis, 50% with Guillain-Barre syndrome, 42% with myasthenia gravis, and 38% with polymyositis. We did not detect such antibodies against autologous cells in multiple sclerosis. In multiple sclerosis there was no correlation between the presence of antilymphocytic antibodies and disease activity or duration. In patients with multiple sclerosis, myasthenia gravis, and polymyositis there was no correlation between the presence of cold reactive antilymphocyte antibodies and abnormalities of T or B cell levels.
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页码:1054 / 1057
页数:4
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