METHOD FOR QUANTIFICATION OF BRAIN, VENTRICULAR, AND SUBARACHNOID CSF VOLUMES FROM MR IMAGES

被引：237

作者：

DECARLI, C

MAISOG, J

MURPHY, DGM

TEICHBERG, D

RAPOPORT, SI

HORWITZ, B

机构：

[1] Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD

来源：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 1992年 / 16卷 / 02期

关键词：

MAGNETIC RESONANCE IMAGING; TECHNIQUES; AGING; BRAIN; VOLUME;

D O I：

10.1097/00004728-199203000-00018

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We describe a simple, rapid, and semiautomated method of MR analysis based on mathematical modeling of MR pixel intensity histograms. The method is shown to be accurate and reliable for regional analysis of brain, central, and subarachnoid CSF volumes. Application of the method t to five young and six older subjects revealed significant age-related changes in regional brain volumes whereas no difference was found for traced central CSF volumes or subarachnoid CSF volumes. We conclude that this is a simple method that can be applied to further studies of quantification of brain structure in healthy aging and brain disease.

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收藏

页码：274 / 284

页数：11

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