REEVALUATION OF THE ACID DISSOCIATION-CONSTANTS OF THE HYDROXYL-GROUPS IN TETRASODIUM 25,26,27,28-TETRAHYDROXYCALIX[4]ARENE-5,11,17,23-TETRASULFONATE

被引：73

作者：

YOSHIDA, I ^{[1
]}

YAMAMOTO, N ^{[1
]}

SAGARA, F ^{[1
]}

ISHII, D ^{[1
]}

UENO, K ^{[1
]}

SHINKAI, S ^{[1
]}

机构：

[1] ERATO, RES DEV CORP JAPAN, CHEMIRECOGN PROJECT, CHIKUSHINO, FUKUOKA 818, JAPAN

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1992年 / 65卷 / 04期

关键词：

D O I：

10.1246/bcsj.65.1012

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The acid dissociation constants of the hydroxyl groups in tetrasodium 25,26,27,28-tetrahydroxycalix[4]arene-5,11,17,23-tetrasulfonate (CALX-S4) were determined at 25-degrees-C by potentiometric and spectrophotometric titration methods. The first acid dissociation constant(pK(a1)) was found to be 3.26 +/- 0.02 (mu = 0.1 with KNO3), which demonstrated a remarkable pK(a) shift due to intramolecular hydrogen-bonding interactions among the hydroxyl groups in CALX-S4. On the other hand, considerably weak acidities were observed on the residual three hydroxyl groups of CALX-S4 (pK(a2) = 11.8 +/- 0.3 (mu = 0.1 with KNO3), 11.3 +/- 0.3 (mu = 2.0 with KCl), pK(a3) = 12.8 +/- 0.3 (mu = 2.0 with KCl), and pK(a4) = ca. 14 (mu = 2.0 with KCl)).

引用

页码：1012 / 1015

页数：4

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