MULTIFIELD SATURATION MAGNETIZATION MEASUREMENTS OF OXIDIZED AND REDUCED RIBONUCLEOTIDE REDUCTASE FROM ESCHERICHIA-COLI

被引：25

作者：

ATTA, M

SCHEER, C

FRIES, PH

FONTECAVE, M

LATOUR, JM ^{[1
]}

机构：

[1] CEN, CC, SESAM, DRFMC LAB, F-85X, F-38041 GRENOBLE, FRANCE

[2] UNIV GRENOBLE 1, LEDSS, F-38041 GRENOBLE, FRANCE

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1992年 / 31卷 / 11期

关键词：

D O I：

10.1002/anie.199215131

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A diiron(II) center doubly bridged by carboxylate groups (see sketch) is present in reduced ribonucleotide reductase according to magnetization measurements the strong antiferromagnetic coupling of the oxidized diiron(III) site consistent with an oxo bridge is no longer observed. Protonation of the oxo bridge during the reduction is postulated. The loss of the resulting aqua bridge then leads to the structural unit shown here.

引用

页码：1513 / 1515

页数：3

共 21 条

[1] REVERSIBLE PROTONATION OF THE OXO BRIDGE IN A HEMERYTHRIN MODEL-COMPOUND - SYNTHESIS, STRUCTURE, AND PROPERTIES OF (MU-HYDROXO)BIS(MU-ACETATO)BIS[HYDROTRIS(1-PYRAZOLYL)BORATO]DIIRON(III), [(HB(PZ)3)FE(OH)(O2CCH3)2FE(HB(PZ)3)]+
ARMSTRONG, WH
LIPPARD, SJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (16) : 4632 - 4633
[2] ASHCROFT NW, 1976, SOLID STATE PHYS, P643
[3] ATTA M, IN PRESS J BIOL CHEM
[4] SQUID MEASUREMENT OF METALLOPROTEIN MAGNETIZATION - NEW METHODS APPLIED TO THE NITROGENASE PROTEINS
DAY, EP
KENT, TA
LINDAHL, PA
MUNCK, E
ORMEJOHNSON, WH
RODER, H
ROY, A
[J]. BIOPHYSICAL JOURNAL, 1987, 52 (05) : 837 - 853
[5] FONTECAVE M, 1989, J BIOL CHEM, V264, P9164
[6] FONTECAVE M, 1992, ADV ENZYMOL RAMB, V65, P147
[7] FONTECAVE M, 1990, J BIOL CHEM, V265, P10919
[8] MAGNETOSTRUCTURAL CORRELATIONS IN MAGNETICALLY COUPLED (MU-OXO)DIIRON(III) COMPLEXES
GORUN, SM
LIPPARD, SJ
[J]. INORGANIC CHEMISTRY, 1991, 30 (07) : 1625 - 1630
[9] INTEGER-SPIN EPR STUDIES OF THE FULLY REDUCED METHANE MONOOXYGENASE HYDROXYLASE COMPONENT
HENDRICH, MP
MUNCK, E
FOX, BG
LIPSCOMB, JD
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (15) : 5861 - 5865
[10] MULTIFIELD SATURATION MAGNETIZATION AND MULTIFREQUENCY EPR MEASUREMENTS OF DEOXYHEMERYTHRIN AZIDE - A UNIFIED PICTURE
HENDRICH, MP
PEARCE, LL
QUE, L
CHASTEEN, ND
DAY, EP
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (08) : 3039 - 3044

← 1 2 3 →