POTENTIAL APPLICATIONS OF FT-RAMAN SPECTROSCOPY FOR DERMATOLOGICAL DIAGNOSTICS

被引：67

作者：

EDWARDS, HGM ^{[1
]}

WILLIAMS, AC ^{[1
]}

BARRY, BW ^{[1
]}

机构：

[1] UNIV BRADFORD,SCH PHARM,BRADFORD BD7 1DP,W YORKSHIRE,ENGLAND

来源：

JOURNAL OF MOLECULAR STRUCTURE | 1995年 / 347卷

关键词：

D O I：

10.1016/0022-2860(95)08560-I

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Raman spectra have been obtained from normal, healthy human stratum corneum, callus tissue and hyperkeratotic psoriatic plaques. Assignments of the spectra have been made and changes in the 1000-1500 and 2800-3100 cm(-1) wavenumber regions have been related to lipid loss in the abnormal tissues but the keratin component is structurally unaltered. The potential of the FT-Raman spectroscopic technique for diagnosis of hyperkeratotic conditions in human tissue is assessed.

引用

页码：379 / 387

页数：9

共 18 条

[1]

Barry, 1983, DERMATOLOGICAL FORMU

[2] FOURIER-TRANSFORM RAMAN AND IR-SPECTRA OF SNAKE SKIN [J].

BARRY, BW ;

WILLIAMS, AC ;

EDWARDS, HGM .

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 1993, 49 (5-6) :801-807

[3] FOURIER-TRANSFORM RAMAN AND INFRARED VIBRATIONAL STUDY OF HUMAN SKIN - ASSIGNMENT OF SPECTRAL BANDS [J].

BARRY, BW ;

EDWARDS, HGM ;

WILLIAMS, AC .

JOURNAL OF RAMAN SPECTROSCOPY, 1992, 23 (11) :641-645

[4]

BARRY BW, 1992, J RAMAN SPECTROSC, V23, P61

[5]

BARRY BW, 1993, SPECTROCHIM ACTA A, V49, P913

[6] EPIDERMAL LIPIDS, MEMBRANES, AND KERATINIZATION [J].

ELIAS, PM .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 1981, 20 (01) :1-19

[7] LIPID THERMOTROPIC TRANSITIONS IN HUMAN STRATUM-CORNEUM [J].

GOLDEN, GM ;

GUZEK, DB ;

HARRIS, RR ;

MCKIE, JE ;

POTTS, RO .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1986, 86 (03) :255-259

[8] EFFECTS OF FREEZING ON HUMAN-SKIN PERMEABILITY [J].

HARRISON, SM ;

BARRY, BW ;

DUGARD, PH .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1984, 36 (04) :261-262

[9]

KLIGMAN AM, 1963, ARCH DERMATOL, V88, P70

[10] DRUG PERMEATION THROUGH HUMAN SKIN - THEORY AND INVITRO EXPERIMENTAL MEASUREMENT [J].

MICHAELS, AS ;

CHANDRASEKARAN, SK ;

SHAW, JE .

AICHE JOURNAL, 1975, 21 (05) :985-996

← 1 2 →