ALGINATE AS IMMOBILIZATION MATRIX FOR CELLS

被引：1374

作者：

SMIDSROD, O

SKJAKBRAEK, G

机构：

[1] O. Smidsrød and G. Skjåk-Bræk are, the Division of Biotechnology, Norwegian Institute of Technology

来源：

TRENDS IN BIOTECHNOLOGY | 1990年 / 8卷 / 03期

关键词：

D O I：

10.1016/0167-7799(90)90139-O

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In recent years, entrapment of cells within spheres of Ca2+ alginate has become the most widely used technique for immobilizing living cells. This versatile method includes applications ranging from immobilization of living or dead cells in bioreactors, immobilization of plant protoplasts for micropropagation and immobilization of hybridoma cells for production of monoclonal antibodies, to entrapment of animal cells for implantation of artificial organs. This review evaluates the potential of this method on the basis of the current knowledge of structural and functional relationships in alginate gels. © 1990.

引用

页码：71 / 78

页数：8

共 29 条

[1]

Andresen I.-L., 1977, ACS SYM SER, V48, P361

[2]

BAILLIEZ C, 1985, APPL MICROBIOL BIOT, V23, P99

[3] ISOMALTULOSE PRODUCTION USING IMMOBILIZED CELLS [J].