ACIDITY IN THE ENDOLYMPHATIC SAC FLUID OF GUINEA-PIGS

被引:11
作者
TSUJIKAWA, S
YAMASHITA, T
AMANO, H
KUMAZAWA, T
VOSTEEN, KH
机构
[1] Department of Otolaryngology, Kansai Medical University, Osaka
[2] Department of Otolaryngology, Heinrich Heine University, Düsseldorf
来源
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES | 1992年 / 54卷 / 04期
关键词
ENDOLYMPHATIC SAC; PH; H+-SELECTIVE DOUBLE-BARRELED ELECTRODE;
D O I
10.1159/000276298
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The pH value and the DC potential in the endolymphatic sac (ES) were measured using H+-selective double-barreled electrodes and the intra- and extradural approach, the pH value in the ES fluid (6.65 +/- 0.12, n = 7) was markedly lower than that in the cerebrospinal fluid (7.39 +/- 0.07, n = 7). Acidity in the ES fluid, under normal (nontreated) conditions may be closely associated with metabolism in the epithelium of the ES.
引用
收藏
页码:198 / 200
页数:3
相关论文
共 18 条
[1]  
Kuijpers W., Bonting S.L., Studies on (Na+-K+) activated ATPase. XXIV. Localization and properties of ATPase in inner ear of the guinea pig, Biochim Biophys Acta, 173, pp. 477-485, (1969)
[2]  
Misrahy G.A., Hildreth K.M., Clark C., Shina-Barger E.W., Measurement of the pH of the endolymph in the cochlea of guinea pigs, Am J Physiol, 194, pp. 393-395, (1958)
[3]  
Sterkers O., Ferrary E., A Miel C., Inter-and intracompartmental osmotic gradients within the rat cochlea, Am J Physiol, 247, pp. F602-F606, (1984)
[4]  
Ikeda K., Kusakari J., Takasaka T., Saito Y., Early effects of acetazolamide on anionic activities of the guinea pig endolymph: Evidence for active function of carbonic anhydrase in the cochlea, Hear Res, 31, pp. 211-216, (1987)
[5]  
Arakawa E., Marcus D.C., Thalmann R., Dependence of endocochlear potential on vascular pH, Hear Res, 31, pp. 1-8, (1987)
[6]  
Morgenstern C., Mori N., Amano H., Pathogenesis of experimental endolymphatic hydrops, Acta Otolarvngol Suppl (Stockh), 406, pp. 56-58, (1984)
[7]  
Silvcrstcin H., Biochemical and physiological studies of the endolymphatic sac in the cat, Laryngoscope, 76, pp. 498-512, (1966)
[8]  
Guild S.R., Observations upon the structure and normal contents of the ductus and saccus endolymphaticus in the guinea pig (Cavia cobaya), Am J Anat, 39, pp. 1-56, (1927)
[9]  
Marovitz W.F., Porubsky E.S., Arenberg I.K., Presence of acidic protein-bound carbohydrates in the endolymphatic sac and duct of fetal, neonatal and adult rats, and adult humans, Ann Otol Rhinol Laryngol, 81, pp. 76-81, (1972)
[10]  
Barbara M., Carbohydrate content of the endolymphatic sac. A histochcmical and lectin-labelling study in the Mongolian gerbil, J Laryngol Otol, 103, pp. 137-142, (1989)