A CONVENIENT SYNTHESIS OF 3-FLUOROTHIOPHENE

被引：13

作者：

ELKASSMI, A ^{[1
]}

FACHE, F ^{[1
]}

LEMAIRE, M ^{[1
]}

机构：

[1] UNIV CLAUDE BERNARD LYON 1,CATALYSE & SYNTH ORGAN LAB,CNRS,UP 5401,F-69622 VILLEURBANNE,FRANCE

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 01期

关键词：

D O I：

10.1080/00397919408012631

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-bromo-3-chlorothiophene 2 underwent nucleophilic aromatic substitution using cyanocupper to give 2-cyano-3-chlorothiophene 3 which, after fluoration with CsF, hydrolysis and decarboxylation gave 3-fluorothiophene 6 in good yield. The electropolymerisation of 6 is also described.

引用

页码：95 / 101

页数：7

共 5 条

[1]

BARNISH IT, 1981, J MED CHEM, V24, P154

[2]

NISHIMURA S, 1958, B U OSAKA PREFECT A, V6, P127

[3] NUCLEAR MAGNETIC RESONANCE OF AROMATIC HETEROCYCLICS .I. PROTON AND 19F SPECTRA OF 2- AND 3-FLUOROTHIOPHENE [J].

RODMAR, S ;

RODMAR, B ;

SHARMA, MK ;

GRONOWIT.S ;

CHRISTIA.H ;

ROSEN, U .

ACTA CHEMICA SCANDINAVICA, 1968, 22 (03) :907-&

[4] EFFECTS OF STERIC FACTORS ON THE ELECTROSYNTHESIS AND PROPERTIES OF CONDUCTING POLY(3-ALKYLTHIOPHENES) [J].

RONCALI, J ;

GARREAU, R ;

YASSAR, A ;

MARQUE, P ;

GARNIER, F ;

LEMAIRE, M .

JOURNAL OF PHYSICAL CHEMISTRY, 1987, 91 (27) :6706-6714

[5] PREPARATION OF FLUOROTHIOPHENE [J].

VANVLECK, RT .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1949, 71 (09) :3256-3257

← 1 →