QUANTITATIVE MAPPING OF OCULAR OXYGENATION USING MAGNETIC-RESONANCE-IMAGING

被引：51

作者：

BERKOWITZ, BA

WILSON, CA

机构：

[1] UNIV TEXAS,SW MED CTR,DEPT RADIOL,DALLAS,TX 75235

[2] UNIV TEXAS,SW MED CTR,DEPT BIOMED ENGN,DALLAS,TX 75235

来源：

MAGNETIC RESONANCE IN MEDICINE | 1995年 / 33卷 / 04期

关键词：

OXYGEN; RETINA; EYE; MRI;

D O I：

10.1002/mrm.1910330419

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Retinal hypoxia is hypothesized to initiate angiogenesis, a leading cause of blindness in developed countries. Attempts to test this hypothesis suffer from the need to use highly invasive oxygen electrodes. In this communication, noninvasive and quantitative mapping of ocular oxygenation using magnetic resonance imaging is demonstrated for the first time.

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收藏

页码：579 / 581

页数：3

相关论文

共 25 条

[1] GROWTH-REGULATION OF THE VASCULAR SYSTEM - EVIDENCE FOR A METABOLIC HYPOTHESIS [J].

ADAIR, TH ;

GAY, WJ ;

MONTANI, JP .

AMERICAN JOURNAL OF PHYSIOLOGY, 1990, 259 (03) :R393-R404

[2] PRELIMINARY EXPERIMENTAL RESULTS IN HUMANS AND ANIMALS WITH A SUPERCONDUCTING, WHOLE-BODY, NUCLEAR MAGNETIC-RESONANCE SCANNER [J].

ALFIDI, RJ ;

HAAGA, JR ;

ELYOUSEF, SJ ;

BRYAN, PJ ;

FLETCHER, BD ;

LIPUMA, JP ;

MORRISON, SC ;

KAUFMAN, B ;

RICHEY, JB ;

HINSHAW, WS ;

KRAMER, DM ;

YEUNG, HN ;

COHEN, AM ;

BUTLER, HE ;

AMENT, AE ;

LIEBERMAN, JM .

RADIOLOGY, 1982, 143 (01) :175-181

[3] SPIN-ECHO AND GRADIENT-ECHO EPI OF HUMAN BRAIN ACTIVATION USING BOLD CONTRAST - A COMPARATIVE-STUDY AT 1.5 T [J].

BANDETTINI, PA ;

WONG, EC ;

JESMANOWICZ, A ;

HINKS, RS ;

HYDE, JS .

NMR IN BIOMEDICINE, 1994, 7 (1-2) :12-20

[4] EFFECT OF VITREOUS FLUIDITY ON THE MEASUREMENT OF BLOOD-RETINAL BARRIER PERMEABILITY USING CONTRAST-ENHANCED MRI [J].

BERKOWITZ, BA ;

WILSON, CA ;

TOFTS, PS ;

PESHOCK, RM .

MAGNETIC RESONANCE IN MEDICINE, 1994, 31 (01) :61-66

[5]

BERKOWITZ BA, 1992, INVEST OPHTH VIS SCI, V33, P3500

[6]

BERKOWITZ BA, 1991, INVEST OPHTH VIS SCI, V32, P2382

[7] MAGNETIC-RESONANCE-IMAGING OF THE HUMAN EYE INVIVO [J].

CHENG, HM .

OPTOMETRY AND VISION SCIENCE, 1991, 68 (12) :976-980

[8] PROTON RELAXATION IN PURE LIQUIDS AND IN LIQUIDS CONTAINING PARAMAGNETIC GASES IN SOLUTION [J].

CHIAROTTI, G ;

CRISTIANI, G ;

GIULOTTO, L .

NUOVO CIMENTO, 1955, 1 (05) :863-873

[9]

DEJUAN E, 1986, ARCH OPHTHALMOL-CHIC, V104, P1063

[10]

GARNER A, 1986, INT REV EXP PATHOL, V28, P249