TRANSLOCATION (5-19)(Q13-Q13) IN A MULTINODULAR THYROID GOITER

被引：10

作者：

CIGUDOSA, JC ^{[1
]}

GUERRA, AP ^{[1
]}

GOMEZ, AO ^{[1
]}

JUAN, JLC ^{[1
]}

GOMEZ, JAP ^{[1
]}

ROCA, OF ^{[1
]}

MIRANDA, JLG ^{[1
]}

机构：

[1] UNIV LA LAGUNA,FAC MED,DEPT PATHOL,E-38071 LA LAGUNA,SPAIN

来源：

CANCER GENETICS AND CYTOGENETICS | 1995年 / 82卷 / 01期

关键词：

D O I：

10.1016/0165-4608(94)00223-X

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We describe the cytogenetics of a multinodular thyroid goiter where 90% of the analyzed cells showed a diploid karyotype with a balanced translocation between chromosomes 5 and 19: 46,XX,t(5;19)(q13;q13). This translocation has been previously described in cases of thyroid adenoma. Our case is the first report of this anomaly in nodular hyperplasia. We discuss its putative role in the neoplastic transformation of thyroid lesions.

引用

页码：67 / 69

页数：3

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