RELEASE OF PROSTAGLANDIN-LIKE SUBSTANCE FROM INFLAMED SYNOVIAL TISSUE OF RAT

被引：5

作者：

ARAI, Y

AIZAWA, Y

机构：

[1] Department of Pharmacology, Tokyo College of Pharmacy, Hachioji-shi, Tokyo

来源：

PROSTAGLANDINS | 1978年 / 15卷 / 03期

关键词：

D O I：

10.1016/0090-6980(78)90128-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Influence of inflammation on the release of prostaglandin-like substance (PG) from synovial tissue of rat was studied. 1. 1) In carrageenin inflammation, PG release was proportional to the increase in synovial tissue weight. 2. 2) PG release was only increased in the later phase of dextran inflammation. 3. 3) Aspirin suppressed PG release from both non-inflamed and inflamed synovial tissues, but hydrocortisone suppressed that only in inflamed tissue. © 1978.

引用

页码：447 / 455

页数：9

共 17 条

[1] PROSTAGLANDIN SYNTHETASE-ACTIVITY FROM HUMAN RHEUMATOID SYNOVIAL TISSUE AND ITS INHIBITION BY NON-STEROIDAL ANTI-INFLAMMATORY DRUGS [J].