A PRACTICAL ROUTE TO (E)-GAMMA-HYDROXY-ALPHA,BETA-UNSATURATED PHENYL SULFONES

被引:38
作者
DOMINGUEZ, E [1 ]
CARRETERO, JC [1 ]
机构
[1] UNIV AUTONOMA MADRID,FAC CIENCIAS,DEPT QUIM C-I,E-28049 MADRID,SPAIN
关键词
D O I
10.1016/S0040-4020(01)87900-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reaction of enolizable aldehydes with p-tolylsulfinylmethyl phenyl sulfone (1) in the presence of piperidine in acetonitrile gave selectively E-γ-hydroxy-αβ-unsaturated phenyl sulfones (2) in good yields. Reaction from enantiomerically pure sulfoxide 1 gave unsaturated sulfones 2 in moderate optical yields (ee= 10-50%). © 1990.
引用
收藏
页码:7197 / 7206
页数:10
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