FAILURE OF APOMORPHINE TO INDUCE DOPAMINE RECEPTOR HYPERSENSITIVITY

被引：15

作者：

FLEMENBAUM, A

机构：

[1] Department of Psychiatry, Louisiana State University Medical Center Shreveport, Louisiana

来源：

PSYCHOPHARMACOLOGY | 1979年 / 62卷 / 02期

关键词：

Apomorphine; Cocaine; d-Amphetamine; Dopamine receptor; Postsynaptic supersensitivity; Serotonin; Sexual differences;

D O I：

10.1007/BF00427133

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A pomorphine, a direct dopamine agonist, failed to induce the so called dopamine receptor supersensitivity. Furthermore, a review of the evidence strongly suggests that the mechanisms involved in this phenomenon are not purely dopaminergic. This phenomenon is more complex than one of simple changes in the sensitivity or number of a particular type of receptor. Also sexual differences were observed and the literature suggest an involvement of serotoninergic mechanisms in stereotyped behavior. © 1979 Springer-Verlag.

引用

页码：175 / 179

页数：5

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