DETERMINATION OF SUPEROXIDE DISMUTASE-LIKE ACTIVITY IN SOME DIVALENT METAL SACCHARINATES

被引：34

作者：

APELLA, MC

TOTARO, R

BARAN, EJ

机构：

[1] NATL UNIV LA PLATA,FAC CIENCIAS EXACTAS,RA-1900 LA PLATA,ARGENTINA

[2] CTR REFERENCIA LACTOBACILOS,RA-4000 TUCUMAN,ARGENTINA

来源：

BIOLOGICAL TRACE ELEMENT RESEARCH | 1993年 / 37卷 / 2-3期

关键词：

SUPEROXIDE DISMUTASE (SOD); SOD MIMIC; METAL(II) SACCHARINATES;

D O I：

10.1007/BF02783803

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The superoxide-dismutase-like activity of a series of divalent metal saccharinates of general stoichiometry [MII(SaC)2(H2O)4] . 2H2O (with M(II) = Mn,Fe,Co,Ni,Cu,Zn) has been investigated using the nitroblue tetrazolium O2- reduction assay. The results show that all these complexes possess the capability to dismutate the superoxide anion generated in the xanthine/xanthine oxidase system. Interestingly, the greatest activity is shown by the corresponding copper complex. The results are discussed and compared with those obtained for native superoxide dismutase, which was tested under the same experimental conditions.

引用

页码：293 / 299

页数：7

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