SERUM INTERLEUKIN-2 LEVELS IN A PATIENT WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS - RELATIONSHIP TO CLINICAL COURSE AND CYCLOSPORINE A THERAPY

被引:17
作者
JORDAN, SC
QUERFELD, U
TOYODA, M
PREHN, J
机构
[1] Pediatric Renal Immunology Laboratory, Ahmanson, Pediatric Center, Cedars-Sinai Medical Center, Los Angeles, 90048, California
关键词
Cyclosporin A; Focal segmental glomerulosclerosis; Interleukin-2;
D O I
10.1007/BF00858831
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
We describe a patient with steroid-resistant focal segmental glomerulosclerosis (FSGS) whose serum interleukin-2 (IL-2) levels were markedly elevated in association with disease activity. With cyclosporin A (CsA) treatment, the patient entered remission and serum IL-2 fell to undetectable levels. After cessation of CsA, the patient relapsed and the serum IL-2 levels were elevated again. Reinstitution of CsA therapy was followed by a partial remission and disappearance of detectable serum IL-2 levels. © 1990 IPNA.
引用
收藏
页码:166 / 168
页数:3
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