AN IMPROVED SYNTHESIS OF NAPHTHOATE PRECURSORS TO OLIVIN

被引：31

作者：

ROUSH, WR

MURPHY, M

机构：

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 24期

关键词：

D O I：

10.1021/jo00050a047

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An improved synthesis of olivin synthetic intermediate 3 is described. The synthesis involves the Homer-Wadsworth-Emmons coupling of 14 and 16, the diastereoselective vinylcuprate addition to enone 20, and the condensation of isocoumarin 25 and methyl acetate. A parallel sequence starting from allyl ether 26 has provided naphthoate 35 that is suitably differentiated for glycosylation studies.

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页码：6622 / 6629

页数：8

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