SUMATRIPTAN IN CHRONIC CLUSTER HEADACHE - RESULTS OF CONTINUOUS TREATMENT FOR 11 MONTHS

被引：46

作者：

EKBOM, K ^{[1
]}

WALDENLIND, E ^{[1
]}

COLE, J ^{[1
]}

PILGRIM, A ^{[1
]}

KIRKHAM, A ^{[1
]}

机构：

[1] GLAXO GRP RES LTD,GREENFORD UB6 0HE,MIDDX,ENGLAND

来源：

CEPHALALGIA | 1992年 / 12卷 / 04期

关键词：

CHRONIC; CLUSTER HEADACHE; SUMATRIPTAN;

D O I：

10.1046/j.1468-2982.1992.1204254.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 32-year-old man received a total of 480 injections of subcutaneous sumatriptan 6 mg for the treatment of acute attacks of chronic duster headache over an eleven-month period. Over 90% of the attacks resolved within 10 min of treatment (average 6.8 +/- 3.4). As a comparison, the average duration of 61 attacks occurring over the same period, but not treated with sumatriptan, was 56.1 +/- 20.8 min. This difference was highly significant. There was no clinical evidence of tachyphylaxis, and there were no adverse effects. This is the first report of a long-term treatment of duster headache with sumatriptan. It is concluded that sumatriptan in this case was an effective and well-tolerated treatment for duster headache.

引用

页码：254 / 256

页数：3