SYNTHESIS OF PYRROLO[1,2-A]INDOLES BY INTRAMOLECULAR HECK REACTION OF N-(2-BROMOARYL) ENAMINONES

被引：52

作者：

MICHAEL, JP

CHANG, SF

WILSON, C

机构：

[1] Centre for Molecular Design, Department of Chemistry, University of the Witwatersrand

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(00)61432-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of N-(2-bromoaryl) enaminones 4, prepared by several different methods, with palladium(II) acetate, triarylphosphine and triethylamine in boiling acetonitrile gave pyrrolo[1,2-a]indoles 8 yields of 50 % - 100 %. The hydroxy-substituted product 8k could be oxidised to the mitosene-like quinone 9 with Fremy's salt.

引用

页码：8365 / 8368

页数：4

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