BLUE-BLOOD OR BLACK BLOOD - R(1) EFFECTS IN GRADIENT-ECHO ECHO-PLANAR FUNCTIONAL NEUROIMAGING

被引：9

作者：

RIGHINI, A ^{[1
]}

PIERPAOLI, C ^{[1
]}

BARNETT, AS ^{[1
]}

WAKS, E ^{[1
]}

ALGER, JR ^{[1
]}

机构：

[1] NINCDS,NEUROIMAGING BRANCH,BETHESDA,MD 20892

来源：

MAGNETIC RESONANCE IMAGING | 1995年 / 13卷 / 03期

基金：

美国国家卫生研究院;

关键词：

MAGNETIC RESONANCE IMAGING (MRI); LONGITUDINAL RELAXATION; HYPERCAPNIA; FUNCTIONAL NEUROIMAGING; FUNCTIONAL BRAIN ACTIVATION;

D O I：

10.1016/0730-725X(94)00136-Q

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Changes in the longitudinal relaxation rate (R(1)) may play a role in the MRI signal intensity increases that have been associated with physiological brain activation, We used gradient-echo echo-planar MRI (GRE-EPI) to test whether physiological activations associated with hypercapnia in dogs were dependent on the delay (TR) between successive images in a time-series, Our results show that, in addition to activation-induced changes in the R(2)* (transverse relaxation including inhomogeneity effects), activation-induced changes in R(1) are significant under certain pulsing conditions. In our paradigm, the R(1) contribution became significant at TR values of 1 s or less.

引用

页码：369 / 378

页数：10

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