DEXAMETHASONE CONCENTRATIONS AND THE DEXAMETHASONE SUPPRESSION TEST IN PSYCHIATRIC-DISORDERS

被引：76

作者：

MORRIS, H

CARR, V

GILLILAND, J

HOOPER, M

机构：

[1] INST MED & VET SCI, DIV CLIN CHEM, ADELAIDE, SA 5000, AUSTRALIA

[2] UNIV ADELAIDE, PSYCHIAT, ADELAIDE, SA 5000, AUSTRALIA

[3] ROYAL ADELAIDE HOSP, ADELAIDE, SA 5000, AUSTRALIA

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1986年 / 148卷

关键词：

D O I：

10.1192/bjp.148.1.66

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The dexamethasone suppression test (DST) has been widely used in psychiatry as a laboratory aid for the diagnosis of endogneous depression; failure to suppress serum cortisol levels is interpreted as confirming a clinical diagnosis of endogenous depression. We found that serum dexamethasone concentrations in this test vary widely and are determinants of the DST response: non-suppression of serum cortisol levels is associated with low serum dexamethasone concentrations, and suppression is associated with high concentrations.

引用

页码：66 / 69

页数：4

共 21 条

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