RADIONUCLIDE IMAGING OF METASTASES FROM RENAL-CELL CARCINOMA BY I-131-LABELED ANTI-TUMOR ANTIBODY

被引：49

作者：

BELITSKY, P

GHOSE, T

AQUINO, J

TAI, J

MACDONALD, AS

机构：

[1] VICTORIA GEN HOSP,HALIFAX,NS,CANADA

[2] DALHOUSIE UNIV,DEPT UROL,HALIFAX,NS,CANADA

[3] DALHOUSIE UNIV,DEPT RADIOL & MICROBIOL,HALIFAX,NS,CANADA

来源：

RADIOLOGY | 1978年 / 126卷 / 02期

关键词：

D O I：

10.1148/126.2.515

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

On immunofluorescence assay, goat antisera reacted with renal-cell carcinomas from 20 patients, but not with adult normal human tissues (including patient's normal kidney). After intravenous injection, the 131I-labeled antibody localized preferentially in metastatic renal carcinoma in 6 consecutive patients. Labeled antitumor antibodies may have the specificity for tumor imaging which current radiopharmaceuticals lack.

引用

页码：515 / 517

页数：3

共 8 条

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[2] CURE OF A MOUSE LYMPHOMA WITH RADIOIODINATED ANTIBODY
GHOSE, T
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[J]. EUROPEAN JOURNAL OF CANCER, 1974, 10 (12) : 787 - 792
[3] ANTIBODIES AS CARRIERS OF RADIONUCLIDES AND CYTOTOXIC DRUGS IN TREATMENT AND DIAGNOSIS OF CANCER
GHOSE, T
TAI, J
GUCLU, A
NORVELL, ST
BODURTHA, A
AQUINO, J
MACDONALD, AS
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1976, 277 (SEP20) : 671 - 689
[4] GHOSE T, 1975, CANCER-AM CANCER SOC, V36, P1646, DOI 10.1002/1097-0142(197511)36:5<1646::AID-CNCR2820360518>3.0.CO
[5] 2-A
[6] TUMOR LOCALIZATION OF I-131-LABELED ANTIBODIES BY RADIONUCLIDE IMAGING
GHOSE, T
TAI, J
AQUINO, J
GUCLU, A
NORVELL, S
MACDONALD, A
[J]. RADIOLOGY, 1975, 116 (02) : 445 - 448
[7] TUMOR IMAGING RADIOPHARMACEUTICALS
PATERSON, AHG
MCCREADY, VR
[J]. BRITISH JOURNAL OF RADIOLOGY, 1975, 48 (571) : 520 - 531
[8] PRIMUS FJ, 1977, CANCER RES, V37, P1544

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