DIFFERENTIAL EFFECTS OF OVARIAN HORMONES ON REACTIVITY TO ELECTRIC FOOTSHOCK IN RAT

被引：73

作者：

DRURY, RA ^{[1
]}

GOLD, RM ^{[1
]}

机构：

[1] UNIV MASSACHUSETTS,DEPT PSYCHOL,AMHERST,MA 01003

来源：

PHYSIOLOGY & BEHAVIOR | 1978年 / 20卷 / 02期

关键词：

Estrogen; Footshock; Ovariectomy; Pain sensitivity; Progesterone;

D O I：

10.1016/0031-9384(78)90071-9

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

Flinch and jump thresholds in response to electric footshock were measured daily in estrous cycling female rats. Flinch thresholds fluctuated cyclicly with greatest sensitivity coinciding with periods of greatest estrogen activity. In ovariectomized animals estradiol benzoate increased flinch sensitivity while progesterone reduced it. In contrast, jump thresholds did not vary cyclicly in intact rats and were not influenced by estrogen or progesterone treatments in ovariectomized animals. These findings indicate that in female rats flinch thresholds are sensitive to ovarian hormone levels and that flinch and jump thresholds are independently modulated. © 1978.

引用

页码：187 / 191

页数：5

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