NEW APPROACHES TO THE TREATMENT OF ONYCHOMYCOSIS

被引：52

作者：

ROSEEUW, D ^{[1
]}

DEDONCKER, P ^{[1
]}

机构：

[1] FREE UNIV BRUSSELS, DEPT DERMATOL, B-1050 BRUSSELS, BELGIUM

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 1993年 / 29卷 / 01期

关键词：

D O I：

10.1016/S0190-9622(08)81837-3

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The purpose of this article is to review the pharmacologic properties of two newer agents, itraconazole and terbinafine, and to assess their clinical efficacy in onychomycosis. Both drugs are effective in treating infections caused by dermatophytes. Itraconazole appears to be more efficacious in infections caused by Candida species. The improved effectiveness of these agents is probably related to their rapid penetration into the nails and prolonged bioavailability at the site of infection.

引用

页码：S45 / S50

页数：6

共 13 条

[1] ALCANTARA R, 1988, Advances in Therapy, V5, P326
[2] ARTIS WM, 1985, P SYMPTOMATIC S FRAN, P61
[3] Cauwenbergh G, 1992, Curr Top Med Mycol, V4, P88
[4] DEGREEF H, 1990, BRIT J CLIN PRACT, V44, P91
[5] FINLAY AY, 1992, BRIT J DERMATOL, V126, P28, DOI 10.1111/j.1365-2133.1992.tb00006.x
[6] SHORT-DURATION THERAPY WITH TERBINAFINE FOR DERMATOPHYTE ONYCHOMYCOSIS - A MULTICENTER TRIAL
GOODFIELD, MJD
[J]. BRITISH JOURNAL OF DERMATOLOGY, 1992, 126 : 33 - 35
[7] ITRACONAZOLE PENETRATES THE NAIL VIA THE NAIL MATRIX AND THE NAIL BED - AN INVESTIGATION IN ONYCHOMYCOSIS
MATTHIEU, L
DEDONCKER, P
CAUWENBERGH, G
WOESTENBORGHS, R
VANDEVELDE, V
JANSSEN, PAJ
DOCKX, P
[J]. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1991, 16 (05) : 374 - 376
[8] ROBERTS DT, 1992, J DERMATOL TREAT, V3, P39
[9] SAMSOEN M, 1992, NOUV DERMATOL, V11, P743
[10] VANDERSCHROEFF JG, 1992, BRIT J DERMATOL, V126, P36, DOI 10.1111/j.1365-2133.1992.tb00008.x

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