ENDOCRINOLOGIC, ULTRASONOGRAPHIC AND CLINICAL FINDINGS IN ADOLESCENT AND ADULT POLYCYSTIC OVARY PATIENTS - A COMPARATIVE-STUDY

被引：31

作者：

GULEKLI, B ^{[1
]}

TURHAN, NO ^{[1
]}

SENOZ, S ^{[1
]}

KUKNER, S ^{[1
]}

OVAL, H ^{[1
]}

GOKMEN, O ^{[1
]}

机构：

[1] ZEKAI TAHIR BURAK WOMENS HOSP,DEPT REPROD ENDOCRINOL & INFERTIL,ANKARA,TURKEY

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 1993年 / 7卷 / 04期

关键词：

POLYCYSTIC OVARY; ADOLESCENT; OVARIAN VOLUME; POLYCYSTIC OVARIAN SYNDROME;

D O I：

10.3109/09513599309152512

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study was performed to compare clinical and endocrine features and ultrasonographic data of adolescent (less than or equal to 18 years old) and adult (greater than or equal to 19 years old) patients with ultrasound-diagnosed polycystic ovaries (PCOs) in our Reproductive Endocrinology outpatient clinic. The adolescent group included 35 PCO patients while 125 were in the adult group. Hirsutism was present in 64.7% of the adolescent group and in 49.6% of the adult group. Menstrual irregularities were detected as oligomenorrhea (42.8%), amenorrhea (20%) and irregular but normal cycles (17.4%) in the adolescent group; the figures for the adult group were 46.4, 8.8 and 23.2%, respectively. These differences were not statistically significant. The mean body mass index of the adult PCO group was significantly higher than the adolescent PCO group (p < 0.05). The endocrine features (estradiol, follicle stimulating hormone, luteinizing hormone (LH), prolactin, total testosterone, free testosterone, 17-OH progesterone, androstenedione, thyroid stimulating hormone, dehydroepiandrosterone sulfate (DHEAS)) and the ovarian volume of both groups were comparable. There was a significant positive correlation between ovarian volume and serum LH, total testosterone, free testosterone, androstenedione and DHEAS in both groups. We conclude that polycystic ovarian syndrome is a disorder with perimenarchal onset, the clinical, endocrine and ultrasound features of which will not change by age, although patients are prone to gain weight as they get older.

引用

页码：273 / 277

页数：5

共 22 条

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