CHANGES IN THE SURGICAL-MANAGEMENT OF ESOPHAGEAL CANCER FROM 1970 TO 1993

PURPOSE: To evaluate the changes since 1970 in the management and outcome of esophageal resection for cancer. METHODS: The records of all 316 patients who underwent esophageal resection for cancer at University of California Los Angeles Medical Center during the years 1970 to 1993 were reviewed, RESULTS: When records from 1984 to 1993 were compared to those from 1970 to 1983, significant decreases were seen in operative mortality (10% to 3%, P <0.01), morbidity (72% to 60%, P <0.05), anastomotic leaks (12% to 5%, P <0.03), and reoperations (20% to 8%, P <0.003), Time spent in hospital and in intensive care decreased 40%. These improvements in short-term outcome were most evident in patients with disease in later stages. The 5-year survival rate increased (12% to 21%, P <0.01), A greater percentage of tumors presented in early stages (21% versus 37%). CONCLUSIONS: Short-term outcome of surgical resection for esophageal carcinoma improved between 1970 and 1993, in part because of changes in perioperative and surgical management, Long-term survival improved, probably due to earlier detection of tumors.