SYNTHESIS OF MACROPOROUS HYDROGELS WITH RAPID SWELLING AND DESWELLING PROPERTIES FOR DELIVERY OF MACROMOLECULES

被引：102

作者：

YAN, Q

HOFFMAN, AS

机构：

[1] SHANGHAI UNIV SCI & TECHNOL,SHANGHAI 201800,PEOPLES R CHINA

[2] UNIV WASHINGTON,CTR BIOENGN,SEATTLE,WA 98105

来源：

POLYMER | 1995年 / 36卷 / 04期

关键词：

MACROPOROUS HYDROGEL; SWELLING KINETICS; PORE SIZE;

D O I：

10.1016/0032-3861(95)93123-4

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Thermally reversible macroporous poly(N-isopropylacrylamide) (polyNIPAAm) hydrogel has been synthesized in aqueous solution at a temperature above the lower critical solution temperature (LCST). Rapid swelling and deswelling kinetics of this macroporous hydrogel are characterized. Pore size measurement by a solute exclusion technique reveals that this macroporous hydrogel has a larger pore size distribution than the hydrogel synthesized at a temperature below the LCST. This kind of thermally reversible macroporous hydrogel will be very useful in delivery of macromolecules.

引用

页码：887 / 889

页数：3